the relationship between the way in which normal hemopoietic stem cells respond to irradiation alone or in the presence of bleomycin sulfate (blm-s) and actinomycin 0 (act-d) was investigated. single doses of blm-s at 0.3 mg/kg and act-o at 0.10 mg/kg body weight were injected intravenously 1-6 hours prior to whole body irradiation and treatment was repeated twice more with time intervals. when...

background: alpha particle irradiation from radon progeny is one of the major natural sources of effective dose in the public population. oncogenic transformation is a biological effectiveness of radon progeny alpha particle hits. the biological effects which has caused by exposure to radon, were the main result of a complex series of physical, chemical, biological and physiological interaction...

ameloblastomas are regarded as a homogeneous group of neoplasms with locally invasive character. they generally do not show induction of dental hard tissue formation except in few cases. biological behavior and histogenesis of these tumors is still unexplored as there is lack of relevant studies and long follow-up of these patients. so, we aimed to report this rare case of dentinoameloblastoma ...

Various mesenchymal stem cells as easily accessible and multipotent cells can share different essential signaling pathways related to their stemness ability. Understanding the mechanism of stemness ability can be useful for controlling the stem cells for regenerative medicine targets. In this context, OMICs studies can analyze the mechanism of different stem cells properties or stemness ability...

background: transplants of multipotent stem cells have been shown to have a neuroprotective effect after central nervous system injury. the bulge region of the hair follicle has been reported as a putative source of hair follicle stem cells (hfsc) for many years; however, few studies have documented the properties of bulge derived cells in vitro until now. this study was conducted to isolate an...

many cellular damages either in normal or cancerous tissues are the outcome of molecular events affected by ionizing radiation. t‑cells are the most important among immune system agents and are used for biological radiation dose measurement in recommended standard methods. the herbs with immune modulating properties may be useful to reduce the risk of the damages and subsequently the diseases. ...